Preheat your oven to 375°F (190°C) and line a baking sheet with parchment paper.
In a large mixing bowl, combine the whole wheat flour, whey protein isolate, baking powder, garlic powder, onion powder, salt, and pepper. Mix well.
In a separate bowl, mix the Greek yogurt and olive oil until smooth. Slowly incorporate this mixture into the dry ingredients, stirring until a dough forms.
Add the shredded mozzarella cheese and chopped pepperoni to the dough, mixing until evenly distributed.
On a floured surface, roll out the dough into a rectangle about 1/4 inch thick.
Cut the dough into strips approximately 3 inches wide. Roll each strip tightly around a piece of pepperoni, starting from one end.
Place the rolled pizza bites on the prepared baking sheet and brush the tops lightly with olive oil.
Sprinkle Italian seasoning over the rolls for added flavor.
Bake in the preheated oven for 15-20 minutes or until the rolls are golden brown.
Remove from the oven and allow to cool for a few minutes before serving with marinara sauce on the side for dipping.